Objectives

  • Discuss how the primary structure of nucleic acids is the order of bases in the polynucleotide sequence, and the secondary structure is the three-dimensional conformation of the backbone.
  • Discuss the monomers of nucleic acids are nucleotides.
  • Discuss how the bases are bonded to the sugars, forming nucleosides.
  • Summarize how nucleosides are linked by ester bonds to phosphoric acid to form the phosphodiester backbone.
  • Specific proteins called single-strand binding proteins bind to the single-stranded regions and protect them from nucleases.
  • Spontaneous mutation of bases and insertion of the wrong nucleotide would normally lead to an error every 104 to 105

Instructions:

Step 1: Read the article found in section 9A: Biochemical Connections: Law in your digital book.

Using the Concorde’s Online Library, your digital material, and other scholarly websites, discuss the following:

  • What are your feelings regarding the article?
  • Describe, in detail, what the following statement means, “What can be patented is purified DNA containing the sequence of the gene and techniques that allow the study of the genes.”
  • How do you see the patenting of genes/DNA impacting science and medicine over the next 30 years?
  • Do you believe this trend is ethical? Why/why not?

Step 2: Compile your thoughts & research and write a 3-5 page paper addressing the topics and questions above.

Step 3: Once complete, save your file and submit.

  • You are required to have at least two outside resources, at the scholarly level. Wikipedia is not acceptable.

Attached as a PDF is the section of the book (Biochemistry 9th edition: 9781305961135).

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